Fortunately, there are many ways to manage pain, whether that means treating the source of the pain or coping with the pain…. Federal officials have set up locations across the country on National Prescription Drug Take Back Day for people go properly dispose of their old…. Health Conditions Discover Plan Connect. Ibuprofen vs. Acetaminophen: How Are They Different? Drug features Brands Ages Cost and availability Side effects Drug interactions Warnings Takeaway Introduction Acetaminophen and ibuprofen are medications used to treat pain and fever.
Acetaminophen vs. Brand-name versions. In children. Cost and availability. Side effects. Drug interactions. Use with certain medical conditions. Talk with your doctor. Read this next. Medically reviewed by Lindsay Slowiczek, PharmD. Medically reviewed by Alan Carter, Pharm. Is Tylenol Acetaminophen Anti-Inflammatory?
Medically reviewed by Darren Hein, PharmD. Pain relief basics. Taking ibuprofen can also increase the risk of heart attack and stroke, especially in those with a history of heart problems or high blood pressure. Ibuprofen should be avoided to treat pain before, during, or after coronary artery bypass graft surgery.
One study found that acetaminophen can cause NSAID-related adverse effects in higher doses over time. These adverse events include ulcers, heart attack, and stroke in some people who are predisposed to these events. Acetaminophen may be considered safer than ibuprofen for pregnancy. However, these drugs should only be taken during pregnancy if the benefits outweigh the risks.
Taking acetaminophen or ibuprofen may cause premature closure of the ductus arteriosus in babies. Acetaminophen is an over-the-counter OTC analgesic and antipyretic. It is used to treat mild to moderate pain and fever in adults and children.
Acetaminophen comes in regular-strength and extra-strength formulations. It comes in over-the-counter and prescription strengths. Higher strengths of ibuprofen are often used to treat chronic pain conditions like osteoarthritis. Acetaminophen is known by the brand name Tylenol and approved to treat pain and fever. Ibuprofen is known by the brand name Advil or Motrin and approved to treat pain, fever, and inflammation.
Ibuprofen also comes in OTC and prescription strengths. Ibuprofen is more effective than acetaminophen for treating inflammation and chronic pain conditions. Ibuprofen is FDA-approved to treat osteoarthritis and rheumatoid arthritis whereas acetaminophen may be used off-label for these conditions.
However, acetaminophen is generally more tolerable than ibuprofen in regards to side effects. Acetaminophen may be safer than ibuprofen for pregnant women. Ibuprofen should be avoided in pregnant women due to the risks of adverse effects.
Consult a doctor if you are pregnant or breastfeeding before taking either medication. Drinking alcohol with acetaminophen or ibuprofen can increase the risk of side effects. Alcohol can increase the risk of liver damage, ulcers, and bleeding when consumed with acetaminophen or ibuprofen. Liver damage is more commonly associated with acetaminophen than ibuprofen. This is because acetaminophen is extensively metabolized or processed in the liver.
Ibuprofen rarely causes liver damage and is not processed as heavily in the liver. Acetaminophen and ibuprofen can be safely taken together for pain relief. Research has shown that acetaminophen and ibuprofen are more effective for treating certain types of pain when combined. However, it is important to consult a doctor since taking high doses of both drugs may lead to adverse effects. Skip to main content Search for a topic or drug. Acetaminophen vs. By Gerardo Sison, Pharm.
Updated on Jan. Want the best price on ibuprofen? Want the best price on acetaminophen? Top Reads in Drug vs. Toujeo vs Lantus: Main Differences and S Dulera vs Advair: Main Differences and S Like any other drug, ibuprofen can have side effects.
One of them is liver damage , though this is rare. As a result, medication can have unintended effects on the liver. To determine the true capacity of ibuprofen to cause liver problems, the researchers regularly administered moderate amounts of ibuprofen to mice for 1 week.
The drug dosage was the equivalent of an adult human taking around milligrams of ibuprofen per day. At the end of the week, the investigators used advanced mass spectrometry — a set of techniques that allow scientists to establish the ratio and type of chemicals present in a laboratory sample at any given time. Aldrin Gomes. The changes were different, depending on the sex of the mice. Meanwhile, in female — but not in male — mice, the ibuprofen regimen increased the activity of some cytochrome Ps, a class of enzyme that contributes to the breakdown of drugs.
Gomes emphasizes. However, many commonly used drugs, such as ibuprofen, are being overused and should not be used for certain conditions, such as mild pain. Moreover, the research team emphasizes a need for more investigations into how drugs affect males, compared with females, as there may be key differences in metabolism between the sexes.
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